. . . To encourage the growth of any science, the best thing we can do is to meet together in its interest, to discuss its problems, to criticize each other's work and, best of all, to provide means by which the better portion of it may be made known to the world. . . .
Deep connections between the very large -- the cosmos -- and the very small -- quarks -- have shaped the Universe we see today and entangled the agendas of particle physics and cosmology. I discuss the present state of cosmology and the big mysteries that point to new physics -- dark matter, dark energy, inflation and the baryon asymmetry of the Universe -- and the prospects for progress.