PHYS 498 EBP - Experimental Biophysics

Fall 2022

Special Topics in PhysicsPHYS498EBP73027LCD41300 - 1650 T R    Paul Selvin
Sharlene Denos

Official Description

Subject offerings of new and developing areas of knowledge in physics intended to augment the existing curriculum. See Class Schedule or departmental course information for topics and prerequisites. Course Information: 1 to 4 undergraduate hours. 1 to 4 graduate hours. May be repeated in the same or separate terms if topics vary.

Section Description

Experimental Biophysics: Physics students in this advanced laboratory course will do 5 experiments that have won Nobel Prizes for their inventors?plus a few more experiments?all related to using physics to understand biology. You do NOT need to know any biology to take the course (but be willing to learn). These will be 1. Optical Trapping (2018); 2. Super-resolution Microscopy (2014); 3. The Luria-Delbruck experimental on fluctuation methods to determine the role of mutations in evolution (1969); 4. The discovery of the 3rd domain of life, Archaea, by U of Illinois Carl Woese (2003, Craaford Prize); 5. The polymerase chain reaction (PCR, 1993); 5. Computational prediction of protein folding (2013, and one shortly!); 6. Electricity in you: Measuring nerve conduction; 7. Optical detection of magnetic imaging using single (quantum) ?bits? of diamonds.